Role of Long Non-coding RNAs in Cellular Stress Response

  • Anshika Goenka
  • S. Ganesh BSBE, IIT Kanpur


The cellular systems are often exposed to variations in their environment and to cope-up with such intermittent changes the cell systems have evolved a variety of pathways to promote cell survival. These pathways often referred to as “cellular stress responses”, involve intricate cellular signaling network and some of which are evolutionarily conserved. Given that such response mechanisms have cascading effects, it is not unexpected that regulatory forms of long non-coding RNAs (lncRNAs) play critical roles in these processes as well. This short review focusses on the recent discoveries role of lncRNAs in the heat shock response in mammalian cells.

Special Section on RNA Biology